Female cats will mate with multiple males in the hopes that the strongest genes will be passed on to her offspring. So a "one and done" situation doesn't really apply to cats.
The only way to make it stop is to have your cats fixed.
Please don't continue to let her mate, as that won't solve your problem and will only create more in the form of kittens, which are going to be rambunctious and expensive to take good care of. The only thing you can do is get your male cat neutered ASAP and get your female spayed once she's no longer in heat. In the meantime, make sure she's secured in your house with no access to intact males, try playing with her to distract her a bit, and get some earplugs. As far as I know, you'll likely just have to wait it out.