Hyperesthesia, Limping, Fever, Lethargy?

Simonalm

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Hello everyone, I'm going to apologize in advance for how long I know this will be. My cat is suffering from a mystery illness that my vet can't figure out.

Quick background, I have an 8 month old male cat named Norman. Indoor only, neutered, up to date on vaccines, tested negative for FeLV when he was a kitten before he met my other cat Simon. I fostered him and the rest of his litter, 2 of his siblings had full tails, 1 had no tail, and Norman and his brother both have stumpy tails. I've stayed in touch will all of his siblings owners and there all doing great! Norman was fine until a month or so ago.

1.5 months ago: one morning he had what my vet though sounded like hyperesthesia, rolling back, muscle twitching, etc. it last 10 mins and stopped. He said if it happened again we would put him on medicine.

1 week later: Another episode of hyperesthesia, so we put him on pre gabalin and it seemed to kind of work. Although his back was still very sensitive and up until the first episode it was not.

1 month ago: Over the weekend (of course), Saturday he didn't wake me up to be fed. Very odd for him but he ate when I fed him. He was very sleepy all day Saturday but would still eat and play if you woke him. His back was also very sensitive (hyperesthesia), but no other symptoms. Sunday the same, except for late Sunday night when I woke him up to be fed he started LIMPING in his back leg, but was running and jumping still?

I took him to the vet first thing Monday. He was running a slight fever, blood work and x rays were perfect however. And of course he wasn't limping when we got there but was as soon as we got back home. They put him on an antibiotic and we were told to continue on the pre gabalin for hyperesthesia.

Within 24 hours, no limping, no lethargy, no fever. He finished his round of antibiotics and within 4-5 days all of those symptoms were back and this time instead of limping in his back leg, its his front leg.

Back to the vet we went, they put him on a stronger antibiotic. We ran tests, my vet thought possibly toxoplasmosis because that can also cause the hyperesthesia too. Every test including toxoplasmosis can back negative.

Again within 24 hours all of his symptoms respond to the antibiotics. So we did a much stronger antibiotic for 2 weeks (today) and now my vet wants him off the antibiotic but kept on the pre gabalin for hyperesthesia long term? I've went my vet for years and have always trusted and respected his opinion but this time he has admitted he has no clue whats going on. He said he's never seen anything like this and recommended a specialist. We live in Northern Michigan, the closest specialist is over 4 hours away.

My problem is that I'm worried his symptoms will return again in 5 days. I also believe that the hyperesthesia is a symptom of whatever is going on and not the stand alone form. I guess, my point of all of this is me wondering if any of this craziness sounds familiar to anyone? Has anyone experienced anything like this? My other cat is perfectly healthy.

To anyone who reads this, thank you!! I appreciate it so much.
 

Mamanyt1953

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What kind of specialist are we talking about? That makes a difference. However, at some point, this may become a necessity, although I do recognize what an effort it will entail. It may be the only thing that will give him any quality of life. I think, neurological? But then, why the fever? Some very ODD infectious vector (a tick fever, etc) that the antibiotics are knocking back, but not DOWN? Maybe... Skeletomuscular (those missing tails...)? But again, why the fever? Whatever this is, please keep us posted on how Norman is doing.
 
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Simonalm

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Thank you guys, I will ask my vet about the consult.

Before these other symptoms started I was convinced it truly was just stand alone hyperesthesia. In fact I didn't know that hyperesthesia could even be a symptom of something else until my vet mentioned that it is a clinical sign of toxoplasmosis. From my own research I've found that it's also a symptom of meningitis but I can't find anything else that it could be a symptom of. After these new symptoms though I've realized the hyperesthesia is a big part of it. When he got really sick those 2 times his hyperesthesia was very much increased.

As far as the specialist, they have vets that specialize in everything! So thats really nice, they do have a neurologist which is what my vet suggested us seeing.

My vet wondered about his tail too, especially when he was limping in only his back leg the first time around His x ray looks normal thought and he doesn't mind it when you touch his tail. This time around his limping switched from his back leg to his front and thats probably my vets biggest concern.

Whatever it is seems to be quite the mystery that responds to antibiotics very well but why is his blood work perfect? So frustrating. Within 24 hours of being on an antibiotic he's back to his normal crazy kitten self. Both times this has happened he hasn't woke me up at 5am to be fed which is his trademark lol so thats always a telling sign.
 

Mamanyt1953

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What a mystery this is! And how frustrating it has to be for you, as well! Your love for him is clear in every word you write. Keep us posted on how he's getting along, and what you are able to find out. We'll fret about him if you don't.
 
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