This is the 1st year that frontline plus is not working at all..Its like I haven't even put it on... I have two Persians and 4 Siamese They all get frontlined regulary ..The Persians get monthly baths also.... I have 1 golden Retriever who gets flea baths and Frontline he has also been on a antibiotic and prendisone for 10 days due to allergy skin..probably from flea Bites........ I do have rugs in the house I vacumm daily sometimes twice.... No signs of fleas in the house just on the pets! I have always used frontline and it has worked well. Not so this year..I'm leary of other topical drops as I have heard Horror stories about other brands.. What else have any of you used with no health issues to the kitties that also have worked? I am thinking I should give another brand a try for a few months and see if this will help...