Spirit and Trouble, both started with chaffed nipples (only the 2 lowest nipples) then Trouble developed a rash on her tail that she keeps chewing at, and Spirit developed a rash between her back legs. These are open oozing wounds, not dry scaly ones. We have treated with an antifungal (in case of ringworm) and with antibiotics, a steriod injection to help with the inflamation and itching, and daily scrubbing with a chlorahexadine solution with no improvement. Today when I cleaned my rat cage I noticed the rats had a pretty nasty case of mites and the mites were on the entertainment center where the rat cage is kept (I have been fighting mice in the walls and I think that is where the mice originated). Now usually Rodent mites prefer rodents but they will bite humans (I was itching while I was cleaning), so now I am wondering if Trouble and Spirit could be sensitive to the mites. Anyone else keep rodents and see anything like this, or ideas of what else could cause these sores? I am going to treat them for mites this week and see if that helps, but after that I am running out of ideas as to what is causing this. Trouble and Spirit do not associate with each other, but Trouble and Sturgis do lay together and Sturgis shows no signs of anything.