Poor Smokie! I'm so sorry he is feeling so terrible. I know you are waiting for the biopsy results, but I would really consider getting a 2nd opinion from a different vet. Maybe call one and tell him everything that's going on, what Smokie is taking, etc. They may have an opinion.
Sending lots of get well wishes for the beautiful Smokie.
Sending lots of get well wishes for the beautiful Smokie.