I had a big problem with spraying cats (I have 15 in the house) I have seen all my cats spray at one time or another--males and females--all spayed and neutered. I have just recently begun using Bach rescue remedy in their drinking water and I switched from tap water to bottled water (unfortunately at the same time) I don't know which change helped but my spraying problems have been cut by at least 90 percent. Two of my cats who have their own room use to spray and pee in all the corners and on the sofa (covered with plastic and slipcover)and on the wall all day every day! Now they still are spraying in one corner but this is a remarkable improvement that I can live with.