I would discuss it with your veterinarian. Here is what I found though:
From their website http://www.us.atopica.com/FAQs/faqs.htm
A. Every atopic patient is different and must be managed individually. In clinical trials, dogs that showed a 50% improvement in skin lesions and pruritus were started on a tapering dose (i.e., same dose every other day) then reevaluated in 30 days. If continued improvement was seen, then twice-weekly dosing was instituted. In the U.S. field trial, 41% of dogs received EOD dosing after 30 days. By week 16 of the study, 42% of dogs were being managed on twice-weekly dosing.
From their website http://www.us.atopica.com/FAQs/faqs.htm
A. Every atopic patient is different and must be managed individually. In clinical trials, dogs that showed a 50% improvement in skin lesions and pruritus were started on a tapering dose (i.e., same dose every other day) then reevaluated in 30 days. If continued improvement was seen, then twice-weekly dosing was instituted. In the U.S. field trial, 41% of dogs received EOD dosing after 30 days. By week 16 of the study, 42% of dogs were being managed on twice-weekly dosing.