Yes, they are big! I break each one into about six or eight pieces and put the pieces on four meals each day. That's not how the label says to dose them but they work really well like that for our cats. And the cats think they're treats. I'm not sure which ingredient(s) make them so effective but I'm really glad I bought them on a whim because of the slippery elm bark!I use vets best. All 3 of my cats like it. They are bigger than what I normally get