Multiple Myeloma ....

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librarycat2022

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Hi,

My cat Odin was diagnosed with Multiple Myeloma Feb. 2021, He was on chlorambucil until January 2022 when it seemed like he had something called Fanconi's syndrome as a result of the Chl- chemo treatment. He did go into remission. He is also on Prednilisone and has been throughout. Everything was going fine and then an eating issue last Friday and the bloodwork makes it seem the MM may be coming out of remission. My vet thinks it may be the time to give him a rest from treatment and let nature take its course- but the oncologist thinks we should try the Chlorambucil again since it seems he had a UTI and may- or may not- have had Fanconi's Syndrome. I ordered the pills but they won't get here until Friday. He needs Entyce and Mirataz to want to eat. I can't find anything on the web saying that a cat can go into remission twice from MM. I want the best for him certainly- but I also don't want to see him leave if he could be happy. still. Anybody have any experience with this or something similar? Thank you!
 

fionasmom

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In humans, MM is rarely curable. It is expected that a relapse will occur; some go through cycles of remission and relapse. If you have been searching the web for the answer about cats, you probably already came across this information. Even in dogs, it is different from cats, so I don't know if the human comparison is helpful or not. Fanconi's Syndrome is also very rare in cats.

THE FELINE CANCER SUPPORT GROUP | Facebook
This is a feline cancer support group that you might investigate


Search Results for Query: multiple myeloma
TCS threads about MM. Some are in the non-cat forums, so mention humans with it.
 
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librarycat2022

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Hi
I don't have experience with that, but wanted to post this thread link just in case it might have something useful;
Any Good Tips To Get Your Cats To Eat? Share Them Here!
Thank you
Hi
I don't have experience with that, but wanted to post this thread link just in case it might have something useful;
Any Good Tips To Get Your Cats To Eat? Share Them Here!
Thank you! I didn't check the notification bell so did not know you responded until now. I read both articles and they are helpful! I'll see if my vet can prescribe me the critical care.
 
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librarycat2022

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In humans, MM is rarely curable. It is expected that a relapse will occur; some go through cycles of remission and relapse. If you have been searching the web for the answer about cats, you probably already came across this information. Even in dogs, it is different from cats, so I don't know if the human comparison is helpful or not. Fanconi's Syndrome is also very rare in cats.

THE FELINE CANCER SUPPORT GROUP | Facebook
This is a feline cancer support group that you might investigate


Search Results for Query: multiple myeloma
TCS threads about MM. Some are in the non-cat forums, so mention humans with it.
Thank you I will read them!
 
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librarycat2022

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fionasmom -

I saw that on another thread you know about Chlorambucil.

Yes- the vet did say Fanconi's syndrome was rare and it was about 2-3 months after Odin getting off of it on Jan. 6- that I would say his eating was back to normal.

In fact he went from 9 pounds to 10 pounds.

Then April 28th- no eating and the blood drawing on April 29th - results on Monday May 2 that seem to indicate the multiple myeloma is coming back.

I did order the Chlorambucil for him again- oncologist prescribed. The oncologist questions whether it was Fanconi's syndrome in January since it took longer than expected to recover from it.

So he has had his second dose today- every other day-first one Thursday. And now- he really is not eating. I gave him the Entyce and the Mirataz and have been putting different foods in dishes for him and he took maybe 3 bites and just is not interested. Also not drinking as much water.

He is sleeping a lot. But I am a little concerned that if it was Fanconi's Syndrome in January I am leading him back to that.

Vet visit on Monday but if anyone has any insight- it will be very appreciated!

Best to everyone!
 

fionasmom

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My Chelsea used Chlorambucil for small cell intestinal lymphoma and was successful with that treatment for over a year. She did not acquire FS, and eventually passed from end stage lymphoma. But I certainly see your point and know you have read the study that shows that 4 cats seem to have developed FS after being given that drug. You have your own experiences with your cat as well. At this point, try to get your cat to eat something; try everything from the list posted earlier. I completely see your point and concern about this going back to where you were. Which vet do you see on Monday? Regular or oncologist?
 
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librarycat2022

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Thanks Fionasmom,

We see the regular vet. I am really lucky as they will give him fluids and are only 20 minutes from where we live. The oncologist- which is through an Emergency Vet Specialist. will not reopen until Tuesday. Odin has been through issues- a few years ago he had to be expressed quite a few times and then was blocked and then had the PU surgery at the Emergency Vet. And now the multiple myeloma.

I want to try this and am hopeful it will work again- but with him not eating today I am so worried I am making things worse for him.
With the pill every other day- I really guess I am in a wait until Monday mode. I will syringe food if I can't get him to eat. I wish I hadn't given the Entyce and Mirataz already- maybe I should have given them hours after the Chlorambucil.

I also have tons of tuna so can see if that can help and will get the critical care food prescription or hopefully be able to get it at the Vet's Monday.

Thank you very very much! It is encouraging to read your comment and advise and has helped me tremendously!
 

fionasmom

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Odin has been through a lot, poor guy. Entyce can cause lethargy, so I don't know i that is part of what you are seeing. When I used it with my last GSD, frequently as he advanced in age, I noticed that it did not work immediately but seemed to take the 4 doses that I was supposed to give him in order to really kick in. I gave it in the morning separately from all his meds (not chlorambucil, but another chemotherapeutic medication). Don't stop the mirtazapine suddenly as it is an anti depressant, even if you were considering changing up your routine with the meds.

I know that at this point you are hoping that something just kicks in and Odin might feel a little bit better. I would do some syringe feeding since this is only mid way through the weekend and your appointment is not until Monday. Please keep us posted.
 
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librarycat2022

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He seems worse since he has been on the Chlorambucil from Thursday. But it seems like there are so many things that could be coincidences with Meds etc. it is hard to isolate things out and know for sure if the Chlorambucil is making him worse, or it is the underlying condition coming out more. He has been sleeping most of the day so I have the food ready to syringe when he wakes up and at this point. I did not know that about the Mirtazapine and anti depression.

I'm concerned about the water too- and how he hasn't been drinking. I hope that is just because he was sleeping so much.

I will keep you posted.

Thank you & Furballsmom for all of the support!
 
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librarycat2022

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Odin update-
I did syringe food & water last night and this morning- but in between- late last night and some today- he will take a couple of bites or licks of other food. I'm not sure what to think. I did give the Entyce and Mirataz this morning and it does not do what it seemed to prior.
He was under the couch most of yesterday and today he is on the couch which is good. I'll take him for the fluids and get the canned food tomorrow.

Thanks again and best to all with their fur babies
 
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librarycat2022

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It did not go well. The cancer was back and his vitals were not good and his heart and breathing were bad- to them. Whether it was Fanconi's syndrome or not responding this time to the chemotherapy they don't know. I expected him to go in just to be hydrated but it did not go that way. I had him euthanized and I hope I made the right choice for him. Thanks for all of your help and I wanted to let you know and stop the thread. I'm signing out but best to everyone
 

fionasmom

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I am so sorry to read this. You did everything that you could for Odin, not just with this last illness, but with his previous care throughout his life. You made the hardest and bravest decision that you could for him. You fought the good fight beside him and now he is at rest.

When a cat passes, we close the thread out of respect. You are more than welcome to post a memorial to Odin in the Crossing the Bridge forum.

Crossing the Bridge
 
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