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I treated my Tember for the kidney failure, and used many things, but never did any vet suggest bupenorphrine. Not sure if any other posters have used it , but I have not seen it suggested for kidney failure. I have heard that they may not feel well, but am not aware that they need a pain...

I have been caring for ferals wherever I live. Where I am now, I have tnr's several successfully. Socialize all kittens I can, and  have found homes for three of them. Two more have become my own indoor boys.  I have a few ferals/strays now who come each day, morning and night, for food, water...

I am sorry that your girl is having troubles. It sounds like you have tried a lot of things to help her.  I have a few suggestions. It might be worth taking her into the vet to make sure she doesn't have a uti..although I see that she has done this for years. Perhaps recently starting again...

HI there!  Several years ago, I had a cat nearly the same age, and she was diagnosed with chronic renal failure.  by joining Tanyascrf site, which has been suggested by Anne with Cats here, I was able to give her more time, and it was so much help you would not believe. Not all vets were...