Pimobendan itself is unlikely to directly cause significant hypotension but used alongside amlodipine and benazepril, the combined vasodilation effect can cause BP to drop too much, especially in a frail cat with poor kidney or heart reserves. Also if he is dehydrated or has low blood volume due to advanced kidney disease or poor appetite, the mild blood pressure lowering effect of pimobendan can become more pronounced.
Are his extremities cold? Is his gum pale? These are signs of low BP.
I would stop these meds gradually. For example, halve the dose of pimobendan, stop benazepril, and reduce amlodipine. Stopping all three suddenly is not ideal due to the risks of rebound hypertension and worsening heart function.
Are his extremities cold? Is his gum pale? These are signs of low BP.
I would stop these meds gradually. For example, halve the dose of pimobendan, stop benazepril, and reduce amlodipine. Stopping all three suddenly is not ideal due to the risks of rebound hypertension and worsening heart function.