A cat could contract C. Perf through several routes. This site summarizes it. Cats can become infected by contaminated food or water, through feces of infeced animals, coming into contact with source of environments outdoors, or having weakened immune systems or pre-existing gastrointestinal issues.Yes, and I'm wondering how does a cat get C. Perf.??? He was on Tylan for over two weeks and still had diarrhea... sometimes watery. :-( His regular vet was on vacation so the partner vet prescribed Metronidazole and Endosorb. He had a couple of almost normal stools but had soft piles of diarrhea in between. Nothing seems to stop the diarrhea. :-( There are only 2 pills of Metronidazole left so he has been on it since 8/21. Oh no, I just looked on the label and it said to give it twice a day! I messed up! Checked my log book and I started out giving it twice a day but then ended up only once a day. I think I know why that happened... I read that you had to give it separate from other meds by 2 to 4 hrs. because of a possible interaction. I wrote the times down and forgot that it was to be giving twice a day. Maybe that's why it didn't stop the diarrhea. I'm old and forgetful... I thought I had been doing a good job but not this. :-(
If your vet is certain that Jengo's diarrhea is caused only by C. Perf, a proper use of antibiotics should get rid of it and his diarrhea should stop once you discontinue the meds. You will need another fecal exam to see if meds have led to resolution. If it's caused by something else, IBD for example, you will need to focus on IBD treatment. Prolonged and incorrect use of antibiotics are dangerous. I made a similar mistake with my boy's antibiotic too. Instruction was to give 2 pills daily for 5 days but each pill was neatly split in two, so I was counting one pill as two for the first few days... Jengo has been on antibiotics for a while now, so it's time to test his feces again.
You are right. Certain drugs have possible interactions, but your vet should know. I always do my research before giving new medicine to find out more about interactions, intervals, side effects, etc.