We had our 6 month old Siamese-tiger cat mix breed kitten spayed in October. When we picked her up, she was wobbly and the vet said that she was probably just recovering from the anesthetics. Days later she continued with this behavior and she has never improved since then. We took her to the vet after seeing she was lethargic one day and they found her to be dehydrated but with no other symptoms and her blood tests and x-ray came back great. She has large pupils, and continued to be wobbly and walking with imbalance in her back legs. In everything I've read online she suffered some sort of brain damage during the surgery and it would never get any better, I found several research papers where Siamese cats are susceptible to a mix of Ketamine/Valium used in surgeries to anesthetize them where it could cause them to have low oxygen during surgery or cause other complications, just something for others to watch for. So we accepted that our poor kitten was special and would be this way. She still had a lot of her personality but just didn't move around as well any more. The vet treated her with Clindamycin antibiotics for 4 weeks just in case she had toxoplasmosis affecting her brain that may have flared up during the surgery. This did improve her attitude, and her lethargy went away but she still had her balance issues. Once we finished the antibiotics our kitten seemed fine, but then started to stagger more and lose her back leg control slowly over several more weeks, and got to the point she wouldn't even try to climb up on our beds and couches anymore either. We again took her to our vet who tried steroids for a few weeks but that didn't help at all so we just assumed this was part of her brain damage and she'd be this way from now on. Then about 2 weeks ago she just totally lost her back leg control. She would try to move her back legs and they would just kick out from under her as if she was trying to jump. Her legs kick fully out extended and she would just flop around on the floor and couldn't get up. We rushed her to the vet but they can't find anything wrong and her blood tests again looked really good. We have her on antibiotics and steroids again now but it's not helping so far. She's now learned not to move her back legs unless she really wants something, but she's basically paralyzed on her hind legs and even her tail doesn't move. She still has bowel and bladder control which is odd if she was fully paralyzed, in fact when she starts kicking on the floor I've now learned she's telling me she has to eat, drink, or go to the bathroom. So I pick her up and carry her to our kitchen and she'll roll over to her food, water, or the cat box to tell me what she wants, very smart kitten for saying she has all these other issues going on. She goes in the litter box just fine as long as I hold her up so she can do her business. I know she's not happy, she doesn't purr anymore and just sleeps a lot or just sits here staring at us. My other cats will come by and she'll still try to play with them or toys in front of her so I know our kitten is still in there somewhere. Our vets are stumped, they recommend doing an MRI but we live in Alaska and would have to fly to Seattle to do this. The cost of the MRI, more vet expenses, a flight, not to mention putting our kitten through all of this has really been hard for us to justify. To do the MRI they have to put her under anesthesia and after our last experience we're just not even sure she'd survive it. In addition, in what I've read online and what my vet has told us, about half of the issues that they might find with an MRI that could be causing these symptoms are not treatable and they might still recommend us to just euthanize her anyway. This week we're taking her in to check her liver function, and try a vitamin B-1 shot but I'm just not very hopeful. Any ideas on what else we could try or ideas on what could be going on if any of you have experienced the same? Thanks for any ideas.