Help! Any Input Or Advice On My Cat's Oral Cancer Vs Infection Appreciated

Zookkeeper

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Hello, and my apologies if I am supposed to make an introduction before posting medical questions. I really need some opinions or advice asap...A little over 3 weeks ago I took my beloved boy Pooky (age 11) to the vet for what I thought might be an abscessed tooth on the lower right side. He was lightly examined (i.e., not sedated or anything) and I was told it was a very hard lump, probably a tumor and that it might probably be oral SCC. To cut a long story short I took him to another vet two days later, his mouth was examined & x-rays taken, I was advised to not do a biopsy because of the dental disease issues in his mouth (he's battled stomatitis for years) so again nothing conclusive - the x-rays showed a large indecipherable mass, which the second vet deemed as most likely cancer but could still be a very bad infection. I brought him home & proceeded to try and treat this as a massive dental infection or bone infection, not necessarily because I'm in denial but because I believe there's a chance & I'm not giving up on him yet if it is an infection. And for the past two weeks, I saw him improve. He's been on Clavamox all this time, and he went from not eating and obviously feeling badly (& taking buprenorphine every 8 - 12 hrs) to eating in his own with a good appetite, growing in energy and stamina, going into his usual routines & taking the Bupe every 24 -26 hrs. We had some problems with the sinuses somewhere in the middle but that cleared up quickly. There was not much change in the lump, but after talking with a vet online (who has been by far more helpful than the local ones) I was advised to add another antibiotic to the mix to see if it could get to work on whatever issues could be going on in there. Getting the additional antibiotic, Orbax, proved lengthy and it was delayed, but Pooky continued to do well while we waited. By this time he was eating very well on his own, and could even keep his tongue in his mouth (it had been sticking out since the whole ordeal began). By Wednesday July 3rd he was doing so well I was epically relieved. Everything was going great. I was able to collect the Orbax but had to switch to a different pain medication, Torb elixir. Then Thurs July 4th, wham, his swelling grew. He obviously didn't feel as well, his tongue started protruding again. He kept up a healthy appetite, but otherwise it's been mostly downhill since Thurs night. He started the Orbax on Fri as well as having to switch pain meds on that day. The swelling has gotten bigger in the jaw and spread up the side of his face and caused some swelling and irritation around the eye and renewed sinus problems. After 48hrs on Orbax the sinus issues have lessened, but that's about it. He still has a good appetite, but obviously doesn't feel well and sleeps all time (of course that might be the Torb) & the swelling is sort of balloon like.
And I'll update this post here because my original draft was written yesterday & I didn't post correctly. As of yesterday evening Pooky has shown some improvement - not much or any change in swelling but he has more energy, less sinus trouble, & seems generally more cheerful & comfortable - he even made a small gesture of reestablishing his position (Pooky is king) with one of the other cats, something he has avoided since falling ill. While i'm so relieved to see him make another comeback I worry about this swelling, so my questions remain the same...

Now to get down to my actual questions & sorry that took so long but I thought I needed to explain the backstory... One of the questions is - Does anyone know if an oral tumor from SCC would sit like that for weeks then just grow overnight like that? Here's something that makes me keep thinking of infection - For the better part of two weeks he would have times of drainage, pus or blood but mostly blood, & afterwards I swear the swelling seemed lesser. A few days ago he yawned and I saw inside his mouth and there were no ulcers or anything causing bleeding in the mouth so it's coming from down in there, can it be that the mouth itself healed but locked the infection in, which is now filling with pus etc and causing this rapid swelling? A question tied to that is, can antibiotics alone really save that problem or must it be drained? (I've read enough about humans having to have such things drained to assume that could be the case). Also I needed to ask what anyone might think of his sudden relapse coinciding with hitting the 14 day mark of clavamox? He's still on it, but its like it just ceased to do much good. I need to add here that Pooky has been on Clavamox and amoxicillin off and on for several years, what are the risks of his building an immune resistance to it & it just not working anymore? He's been on Orbax & Baytril before too, just not as much. And by today, the 3-day mark, Orbax must be helping him to get some of these positive reactions. I was advised by the online vet today to keep him on clavamox & orbax, but still not sure now with the clavamox...

Again I'm very very sorry over this long and probably very garbled post, but I am desperate for answers i'm just not getting from non-commital vets or from literally hours of online research. I know if this is cancer i'm going to have to face it & do what's best for him, but I don't want to loose my boy over what could still be a curable infection. And I still believe it could be. It's so much like a much worse version of some of his infections from his stomatitis in the past.
Apologies again and thanks to anyone who could answer even one of these questions!
 

neely

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First, welcome to TCS! :wave3: Please don't worry about making an introduction right away, you can do that when you're ready here: New Cats on the Block

I'm sorry that Pooky is having dental disease problems. Our last cat had oral cancer, i.e. cancer of the mandible and she went downhill quickly. We took her to a dental specialist, is that possible for you to do? She was put on piroxicam which I had to get from a compound pharmacy but it definitely helped with pain and swelling. She also had no side effects from it. I'm not sure I would feel confident with an on-line vet treating my cat, just my personal opinion but you know Pooky best and need to do what you feel most comfortable with for him.

Here is an Article on Stomatitis in cats that may be helpful for you:
Gingivitis And Stomatitis In Cats

Best of luck, sending healing vibes your way for Pooky. :vibes::vibes::vibes:
 
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Zookkeeper

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Thank you for your answer and your concerns for Pooky. I'm so sorry to know you lost your cat in this way, you have my deepest sympathies.

Oh no, I'm not doing all Pooky's vetting through an online vet, I've just gotten some extra suggestions from her. A lot of what she says made sense, but I've sort of mediated between her and my usual vet. Both have been helpful and not helpful. I unfortunately don't have a dental specialist in the area, but I will try to research how far away one might be. I will add piroxicam to my list of recommendations, and have a look at the article, thank you!
 

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Hi and welcome to TCS!

I lost my cat to an oral carcinoma (SCC), and after a course of chemo and radiation therapy, she was put under antibiotics and metacam.
What I can tell you is that the hard lump she had was more or less visible according to the effectiveness of the antibiotics.
So it is possible that, if Pooky has an SCC, the antibiotic is just keeping the infection under control and the swelling might seem to improve.

I do hope it's something else, an SCC is an evil thing to deal with...
 
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Zookkeeper

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Thank you for your reply, and your hopes for Pooky. Any bit of information is helpful to me! I'm so sorry you lost your cat to SCC, it is indeed a horrible thing to face.
 

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I don't have any advice for the possible oral cancer, but when my kitty had recurring dental infections, which caused severe swelling in his face, including a very hard lump in his gum that also ulcered. The antibiotic that worked for him was Antirobe. It is used for mouth and bone infections in cats. I'm not sure if it's in the same family as the orbax or not but just wanted to let you know.
 

fionasmom

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I lost a cat years ago to SCC in the mouth and my story is similar to Antonio65 Antonio65 , sadly. My vet has always used clindamycin for anything in the mouth as Jem Jem mentioned. I have used clavamox often, normally for bladder infections in the case of one of my cats who is diabetic. As for resistance to a long term antibiotic, possible.
 
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Zookkeeper

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Thank you for these replies, they've been extremely helpful. Jem and White Shadow, I had forgotten about Antirobe/Clindamycin being one of the first choice antibiotics for dental, although I know he's taken it successfully in the past. Thanks Jem for mentioning that your kitty also had a hard lump, I was sure that it could occur without being an actual tumor, but hearing a first hand account is something I needed, & thanks White Shadow for pointing out the core name and use!

Fionasmom I'm so sorry to hear of your cancer loss & give you all the best thoughts for your diabetic kitty. Thanks for your agreement on the possibility of antibiotic resistance, I'm having a hard time getting the vets to cooperate with that one...

Pooky has been getting gradually better again, showing more energy & seems more upbeat, I just wish this swelling would go down!
 
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Zookkeeper

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I don't have any advice for the possible oral cancer, but when my kitty had recurring dental infections, which caused severe swelling in his face, including a very hard lump in his gum that also ulcered. The antibiotic that worked for him was Antirobe. It is used for mouth and bone infections in cats. I'm not sure if it's in the same family as the orbax or not but just wanted to let you know.
Hello again, I have a quick question for you, Jem (or anyone who might know) Was your kitty's Antiobe/clinda dosage a lower dose (around 5 - 5.5mg/lb) every 12 hrs, or a higher dose (around 10-15mg/lb) every 24hrs? The vet has him on the higher dose every 24hrs, but given the incompetence I've dealt with so far (I.e., he forgot he's had Pooky on pred non-stop for several years) I wanted to see what the experience or opinion is on here...

Thanks to anyone who might know - Pooky is doing better this week, with a hearty appetite and even some activities, though the lump/ swelling remains (it may have gone down just a bit but I can't yet call that aa anything but wishful thinking) He's only approaching the 48hr mark on clindamycin tonight so I know its early to look for results, as well as the fact osteomyelitis can take months of antibiotic treatment to clear, but after weeks now of dealing with this while trying to squeeze experimental antibiotics from the clinic, I don't want to risk them goofing up on his treatment!
 

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I have a quick question for you, Jem (or anyone who might know) Was your kitty's Antiobe/clinda dosage a lower dose (around 5 - 5.5mg/lb) every 12 hrs, or a higher dose (around 10-15mg/lb) every 24hrs?
I'm really sorry but I can't remember completely, I asked my husband as well. We think it was (liquid Antirobe, oral) once a day, but I don't remember how much. If I can find the receipt, I'll let you know for sure.
 

white shadow

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.
I can't speak for mine - I no longer have the cat's weight at the time it was prescribed.

The Package Insert has this:
Cats:
Infected Wounds, Abscesses, and Dental Infections
5.0 - 15.0 mg/lb body weight once every 24 hours depending on the severity of the condition.
Duration: Treatment with ANTIROBE AQUADROPS oral solution may be continued up to a maximum of 14 days if clinical judgment indi cates. Treatment of acute infections should not be continued for more than three to four days if no clinical response to therapy is seen.
Dosage Schedule:ANTIROBE AQUADROPS, to provide 5.0 mg/lb, administer 1 mL/5 lbs body weight once every 24 hours; to provide 15.0 mg/lb, administer 3 mL/ 5 lbs body weight once every 24 hours.
https://www.zoetisus.com/_locale-assets/mcm-portal-assets/msds_pi/pi/antirobe.pdf

Unrelated to your question is that this stuff is well known to cause diarrhea - you might consider a probiotic dose once/twice a day, 'away from' the a/b.

(I wouldn't be concerned about using the higher end of the strength range.)
.
 
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Zookkeeper

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I'm really sorry but I can't remember completely, I asked my husband as well. We think it was (liquid Antirobe, oral) once a day, but I don't remember how much. If I can find the receipt, I'll let you know for sure.
Thank you though! Yes, so far in researching online 90% of the info says once a day for cats, twice a day more often for dogs (in oral administration anyway, liquid or tablet) so between the vet, the research and you and your husband both thinking it was once a day, hopefully I can rest easy he's getting the right dose. So thank you so much for your reply, even without the receipt!
 
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Zookkeeper

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White Shadow I'm so sorry I missed your reply - thank you very much for the info, I really really appreciate it! I'm much more comfortable with the dosage with the extra back-up info, thank you.
 
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