We have a cat at the shelter that the vet has put on Amatriptalyne. She is the most high strung cat I have ever seen. She had had a long term URI and that is part of why he perscribed it for her. I would normally go the more natural route, but this poor cat is so miserable that I felt it was more compasionate to try and help her feel better emotionally. She screams any time anyone comes near her and will lunge and try to slap. She just had blood work this week and it is totally normal. I'm just wondering if anyone had any experience with this drug for behavioral issues?