I'm curious how your cats react when you take them to the vet. We have a 30 min. drive to get to our vet. We had to go to another location for Wes and he was so calm they came out and said he slept while being examined for HCM heart disease so that was as easy as it gets! More importantly he came out negative for the disease but he still has a heart murmur. Our other one Samson when going to our vet for a regular checkup meowed the entire way there and the entire way back. While he's otherwise gentle with strangers he was hissing and stressed through the exam. As for him I wonder what could calm Samson so he's not so stressed when we need another trip to the vet?