Eight week old kitten, seizures

flcat

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OK, this is a little long, need some crowd sourcing help.

Kitten, caught her when she was five weeks old. First saw her about a week before, noticed she was trying to eat dry food I leave for a colony. Though it was odd but oh well, she has two littermates that are still there, but act normal as I am use to seeing.

Caught her on a Sunday 9/26, on 9/27 took to vet, she had mange and hook worms, she got Ivermectin. Next day on 9/28, she was developing a large tummy, diarrhea started to get severe, had tremors, small focal seizures. Took to vet on 9/29, CBC, xray, vet gave diagnosis of FIP. I ordered for fluids to be put in her, anti biotics, basically supportive care.

Hospitalized until 10/2, vet said there is positive response to the supportive care, diarrhea seems letting up, energy etc, diagnosed changed from FIP to low protein caused by IBD and infection. On 10/3 (a Sunday), I went to emergency vet due to rapid breathing, panting, diarrhea very bad. Emergency vet also said probable FIP, but I wanted just fluid in her to get to my vet on Monday.

10/4, to vet, diagnosed back to FIP, by then I was already communicating with a group that treats FIP. I order supportive care again, but wanted a chem analysis as part of the FIP treatment, and the FIP diagnosis did not sit well with me as being correct. I also order for abdominal fluid to be extracted and tested.

10/5, back to the vet, good news, not FIP, there is no fluid, there is severe intestinal blockage. Kitten on meds, will be good to go for next day. Next day, 10/6, she is like way better, blockage cleared, some meds for things, all fine. The rest of the week she is normal. I needed a Panleuk vaccine and mange treatment though, but Panluek because I had a positive cat in my house recently, so I rolled the dice to get it, because the Panleuk source is unknown, and it would kill this kitten. She was on a resctricted diet, but had to increase the food because she started going insane, and even had focal seizures, she calmed down when I increased the food past what the vet said to.

I forgot when in all of this, but she got an injection of Dex for her breathing, xray showed like Bronchitis, her breathing did get better after this, though often rapid.

10/8, cleared for the vaccine and Ivermectin and got it, within 12 hours, had severe seizure, total episode was 15 minutes. Since then until now, have had four seizures, average one every three days. She had constipation, gave a dose of laxatone, she had a seizure within 20 minutes, another one several hours later.

Blood tests are attached. Went to vet on 10/18, decided bile acid test to test for liver shunt. She had a seizure at 7am on 10/20 after 10 hours of fasting, though thi seizure total episode was 8 minutes or so. Bile test came back negative.

At this point, I am still think the seizures are related to her condition she had. We are giving her Lactulose and Metro for one week to see if it has any effect. If it does, then suspect liver related still on the table, if not, then go see a neurologist.

So, pretty much all this time, and especially now, the kitten has always been energetic, eats, drinks fine. Fast breathing is intermittent as is a fever that comes quickly maybe once, twice a day, but maybe not at all now. No issues found with heart. No fluid accumulating anywhere. She had constipation, but has since been resolved with the meds she is on. Urinating fine. She has these occasional tremors, maybe fast paced robotic type movements when looking at things, taking interest in them, hard to describe. Eyes look normal.

I looked at the blood work issues, many causes of the high and low levels, but she does not display the common symptoms that are associated with them. Mainly, she eats, drinks, plays great, tons of energy.

Does anyone have any insight into all of this, taking into consideration her history, current issues, and the blood work?

I just feel it is related to her condition, the seizures, her tremors, changed over the course of the treatment. I just do not think it is a coincidence.
 

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mrsgreenjeens

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I am just bumping this up for you to get it at the top of the list again. One thing that might be helpful though is to tell us what happens during the seizures. I have read a few threads about cats having seizures, but not with a history like this little guy :frown:

Just because, here is a query I did for thread with seizures in the title: Search Results for Query: seizures

If you read them you might find something of interest, if you haven't already done so.
 

FeebysOwner

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Hi. I was trying to respond as much as I could when this site went down. The first things that come to mind is to ask your vet about kitten bone growth impacting the ALP number. Since it is the only element related to liver function that is skewed, it would seem possible that it is being affected by her growth being such a young kitten. The glucose can be impacted by stress, although it is possible that is also affected by her food, as could be the case with the calcium and phosphorus.

Her blood tests show 'odd ball' results, in that only one number is off and there are usually correlative numbers - that could depict some sort of specific condition - that are normal. The phosphorus can be high from a bleeding disorder, so that might have some connection with the low platelets?

Overall, you might want to ask the vet to re-run the bloodwork to see how the numbers come out a second time.

You might also want to ask the vet about consulting with a vet university or specialty group, either of which - because of their level of expertise and studies in unique cases - might have some experience/knowledge that your vet doesn't have just because it is quite common for the former groups to be exposed to a wider array of situations/cases that many times a vet rarely, if ever sees, in their entire career.

Please keep us posted.
 
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flcat

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I am just bumping this up for you to get it at the top of the list again. One thing that might be helpful though is to tell us what happens during the seizures. I have read a few threads about cats having seizures, but not with a history like this little guy :frown:

Just because, here is a query I did for thread with seizures in the title: Search Results for Query: seizures

If you read them you might find something of interest, if you haven't already done so.
Hi, her seizures start off with twitching, like focal seizures, then turns into a general one with the entire body going crazy, the general one lasts like a minutes to three. After that, quiet, she meows, starts running, and running, and running, twice if I recall, she went back into a short general seizure, then back to running, meowing, etc. Then all stops, she looking around, like she scared of every little thing, or too hyped up by it.

After her general seizure, towards the end of the episode when she running around, she actually knows you are there, she responds to hand movement, sounds, etc, yet seems, well is, out of it.

The entire thing lasts about 15 minutes, then she will either sleep for a long time, or rest a little and pop up as if nothing ever happened. She also will get hungry and start searching for food.
 
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flcat

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Hi. I was trying to respond as much as I could when this site went down. The first things that come to mind is to ask your vet about kitten bone growth impacting the ALP number. Since it is the only element related to liver function that is skewed, it would seem possible that it is being affected by her growth being such a young kitten. The glucose can be impacted by stress, although it is possible that is also affected by her food, as could be the case with the calcium and phosphorus.

Her blood tests show 'odd ball' results, in that only one number is off and there are usually correlative numbers - that could depict some sort of specific condition - that are normal. The phosphorus can be high from a bleeding disorder, so that might have some connection with the low platelets?

Overall, you might want to ask the vet to re-run the bloodwork to see how the numbers come out a second time.

You might also want to ask the vet about consulting with a vet university or specialty group, either of which - because of their level of expertise and studies in unique cases - might have some experience/knowledge that your vet doesn't have just because it is quite common for the former groups to be exposed to a wider array of situations/cases that many times a vet rarely, if ever sees, in their entire career.

Please keep us posted.
She was, gets, very, extremely stressed during the blood drawing, I read the same thing regarding the readings, in that stress can cause it, and absent of those associated readings that would indicate an issue, seems probable it is related to stress.

Also read about the bone growth stuff, and well, she is a growing kitten! Plus all her other liver enzymes are normal, so no readings related to it.

Yes, the low platelets is what making me wonder about things, I went through the list of stuff and it just seems so many lack of symptoms associated with things that cause low platelets, and everything I read seems oriented towards being severely low, not just "low".

But circling back to platelets and bleeding disorder, perhaps related to the condition she had? Her stool is not black though, and her symptoms are just, well, just does not define these things. Her symptoms, all no matter what are:

-seizures
-intermittent fast breathing, she had it way worse with the blockage, still there after, an injection of convenia seemed to effect it. An xray showed a slight bronchitis, made sense because I jsut went through treatment for another kitten with a bad case of bronchitis, and he was fast breathing while resting, plus they are from the same colony though never knew each other there.
-Had an intermittent fever, but it has been a few, several days since last noticed, never showed a fever at the vet.
-eats, and she does have a good appetite, does not really drink but not because medically not want to, seems not like it, back when giving KMR, she would lick it all up. Currently mix water with her food.
-tons of energy, plays, hunts, normal kitten stuff, plays with my other cats, bossy girl.
-four xrays during all of this, never shown any issue with heart or anything other than the blockage. No fluids around lungs, two vets have stated this.

Other than the above and the blood work, I am jsut baffled, my vet seems so as well. We have her on the metro and lactulous, see if that has any effect. She had a seizure today, about two days out from her first dose of those meds. Several things point to infection also, yet not much symptoms of it either.

Yes, specialty vet is next, vet was talking about going to a neurologist, but wondering if a specialty vet, like at the University of Florida (I am in Miami) I should go to? I also feel I need to get this done ASAP.

I am just not feeling based on everything, it is some congenital brain issue, I feel there is something, infection, organ, something, causing it. She did not have seizures like this before her treatment for blockage, they only started after.
 

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Yes, specialty vet is next, vet was talking about going to a neurologist, but wondering if a specialty vet, like at the University of Florida (I am in Miami) I should go to? I also feel I need to get this done ASAP.
There might be a possibility of a closer specialty vet - check on Blue Pearl (bluepearl.com) and see if they have any locations closer. I went to one in Maitland (central Florida). They are actually Affiliated Veterinary Specialists, just operate under the Blue Pearl umbrella. I took Feeby there for a multitude of tests and while they were expensive, I was comfortable with the processes and analyses. I dealt with an internal med specialist, but I know this group also has a neurology department too. You can check out if there are any Blue Pearl locations near you, but do your due diligence in investigating them, just because this organization appears to have absorbed a number of independently operated specialty groups. There might be other specialty groups that still operate independently that are closer to you than UF - I would have thought your vet might have had some ideas about that.

However, your kitten might be better served with UF, just because of unusualness of her situation. It was my understanding that some upfront work related to your kitten might be able to be done with your vet and UF before it comes down to having to take her there. Ask your vet about this aspect.
 
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flcat

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There might be a possibility of a closer specialty vet - check on Blue Pearl (bluepearl.com) and see if they have any locations closer. I went to one in Maitland (central Florida). They are actually Affiliated Veterinary Specialists, just operate under the Blue Pearl umbrella. I took Feeby there for a multitude of tests and while they were expensive, I was comfortable with the processes and analyses. I dealt with an internal med specialist, but I know this group also has a neurology department too. You can check out if there are any Blue Pearl locations near you, but do your due diligence in investigating them, just because this organization appears to have absorbed a number of independently operated specialty groups. There might be other specialty groups that still operate independently that are closer to you than UF - I would have thought your vet might have had some ideas about that.

However, your kitten might be better served with UF, just because of unusualness of her situation. It was my understanding that some upfront work related to your kitten might be able to be done with your vet and UF before it comes down to having to take her there. Ask your vet about this aspect.
I will check around, I just know this gets expensive, and I would not mind except I just do not like tossing things and seeing what sticks, and paying thousands to do it. She has been through so many blood draws, injections, etc, I do not want to repeat all fresh this stuff.

My vet does have referrals, so will see if she works with them to transfer records and information over to them to build on. Plus maybe she can ask them to give me a discount, or at least not rip me off.

I think that is why I defaulted to UF, because I know of them, so if I am going to spend thousands on this, I feel more comfortable doing it with an organization I am familiar with at least.

But I am really hoping something comes through on this, some diagnosis, some "ah-ha" moment. I putting a spreadsheet together, hoping this assists in correlating some symptoms. The blood tests just do not make sense to me, they are a vast improvement over ones a week or so earlier, but I even went back to the vet to verify they were the correct ones, they were, and mine were the only tests ran that day at that time. I also watched them do it, print it out and everything.
 

mrsgreenjeens

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Veterinary Schools are usually up on all the latest and greatest, so I would go there if possible, and definitely have your Vet discuss the case with them first, send all records, etc. to avoid any duplications. OR, ask your Vet to consult with them on this case.

Keep us posted please.
 

Melissa Kellison

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I admit, I am just throwing something at it (to see what sticks); but I also hope throwing something that hasn't been thought of yet will bring you closer to a solution. Could this be caused from toxic exposure while she was out on the street? Mold or something else? How long would symptoms persist for a toxin? What about physical damage and lifelong disabilities?
Some molds may cause seizures.
 
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