Cat has been losing weight but vet can't find anything

halfamill

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75 days ago I took my 11 year old cat to the vet because I saw that she was losing weight and she can't/won't eat any solid foods. She will only eat recently opened wet food. She struggles to eat like something is bothering her mouth. She won't groom herself. They took x-rays and blood work and nothing shows up in her results. I took her again 2 weeks later and they prescribed Mirataz but she still struggles and it makes her vomit. Hoping that she would improve I waited a month and took her to the vet again and they did a thyroid test which again showed up negative. The next test they recommend is a GI test. I already spent over $1000 and it's frustrating to see no improvement. Does anyone know what my next step should be?
 
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silent meowlook

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Is there any way you can post the results of the blood work?
When your cat was at the vet, did they fully examine her mouth?
 

silent meowlook

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Hi. I think you need to have your cat see a specialist to determine what is going on. Probably an abdominal ultrasound would be the next step. Something is clearly not right. The only abnormalities I see in the blood is the increase in platelets which can be caused by many things including Maxine error if done in house. I hope they confirmed this with a blood slide.
The problem is that many regular veterinarians are not equipped and don’t have the knowledge to treat complex diseases in cats. The weight loss is clearly showing there is a serious problem that needs to be discovered, and your best bet would be with a specialist doing more imaging to discover what that problem is.

I am not a vet and this is just my opinion, but you could go down a rabbit hole of spending more and more money without a diagnosis if you don’t get a specialist involved.
Please keep us updated as to what happens.
 

Antonio65

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A dental issue might be invisible if the vet only look at the teeth. The problem might be below the gum line. To see something under the gum line, a vet need to take an X-ray of the mouth and teeth, but they need a dedicated machine to go in the cat's mouth.

This is what a teeth X-ray may look like, a small image of a tiny portion of the cat's mouth. This is what the dentist saw in the mouth of a feral cat of my colony. He had 6 teeth pulled when the dentist noticed that he had some bad teeth by looking at the roots.

Romeo X-ray.JPG


You say your cat looks like she has something that is bothering her mouth. Does your cat let you inspect her mouth? Can you look at her gums, mouth and throat and see if there's anything inflammed or reddish? Can you check the inner sides of her cheeks, and under her tongue?
 

BellaBlue82

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I may be missing it, but did your vet also check glucose levels? My GA cat Nico had lost 3 lbs in 3 months, very tired and not eating a lot. We were very concerned. Vet did blood work with a glucose check and found he had onset diabetes. It still may be dental related, but just wanted to mention in case you still aren't finding any dental issues to be the cause.
 

Meowmee

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I don’t know what is going on it could be a lot of different things. First in my mind is cancer. Her bw looks good but eosinophils are a bit low. I found this link. I hope you get this figured out soon 🤗

If you think something is going on in her mouth, I definitely would investigate that further too.

by the way, my Merlin had good bw the day he was diagnosed with pneumonia… he didn’t receive the right treatment and they didn’t figure out anything that was going on so he didn’t get the right drugs and he died a week later. I had to do a necropsy to know what happened, it turned out, he died from toxoplasmosis pneumonia. He may have had cancer too.

Now my other cats are being treated for it too, with many struggles, I am still trying to get the right version of meds for all three. I am praying they don’t die too.

 
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halfamill

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Thanks for the replies guys. I think will go with the specialist route. I'm new to that and just afraid of it going through several tests without finding anything again. I feel like there wasn't a lot of emphasis on her mouth in her previous visits. A couple of things I forgot to mention. She hasn't been grooming. At the start she would look at her dry food like she wanted to eat but wouldn't. And she doesn't clean her mouth well. Sometimes she'll vomit and I'm not sure if it's from swallowing her food instead of chewing. Here is a video of her after eating today.
 

louisstools

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Dental examinations can be difficult if the cat is not sedated and is a fighter. My angel boy had a nickel sized hole in the roof of his mouth that a vet missed doing the dental part of a routine exam when I brought him in. He didn't get better so I brought him in a week later and a different vet just managed to get a glimpse of it. That hole was large enough that it was obvious...but if the cat isn't cooperating they can only see what they see.

I don't think cats really chew much. Sometimes if they eat too fast they'll vomit.

H halfamill the video didn't post.
 

FeralHearts

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I agree with the others but would like to add something.

Getting her to eat is going to be paramount. Since the mirtazapine is failing is there something else they can try?

Is there an indication she could be nauseated? If so maybe ask for Cerenia?

She needs to keep her strength up for everything ahead.

XO
 

fionasmom

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This may or may not help, but cyproheptadine and Elura are two other appetite stimulants for cats. Elura is specifically for CKD cats.
 

PushPurrCatPaws

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I would go to a internal medicine specialist for sure. Have any of the vets looked into the possiblity of ulcers; or even any issues or diseases dealing with the esophagus? It could be another thing to check.

PS- Some cats do not do well using Cerenia. My previous cat had a lot of negative reactions to it. For her nausea, we used Anzemet.
 
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