D-mannose For E Coli Utis?

Anybody use D-mannose to help rid E Coli from your cat's bladder? Feeby has ongoing UTIs that have all been testing positive for E Coli. I would like to try something that might help to prevent future UTIs so that she is not repeatedly on antibiotics.

If so, what brand/product do you use? If not that, something else?

Thanks!

Here are a couple of posts with info about D-Mannose, but hopefully someone with more specific use of it can answer your question more directly

I Have More Trust Issues Than This Feral..

Managing Idiopathic Cystitis?

I also did a search on 3 words - d-mannose, UTI, E Coli and came up with some active members who I believe used D-mannose specifically for E Coli related UTIs. K KarenF , @cat princesses, @stephanietx (last member suggested it directly to me in a previous thread I started and forgot about ).

There was also another thread that a no-longer active member said there are side effects that are worse than the UTIs. When I was reading about it, I didn't come across side effects, so now I am concerned about that aspect.

If the above members - or any others - can share more about use of it with their cats specifically for E Coli UTIs and whether or not they saw side effects, I would be very appreciative!!!

I am looking at Wellness Partners UTI Pets Pure D-Mannose (don't want to include cranberry, and so many of them especially for pets have this ingredient - not to mention other unnecessary contents).

I also emailed my vet and asked his opinion about D-mannose as well!

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Hey!

This may broaden your understanding: Tanya's Comprehensive Guide - D-mannose.

(In fact, the entire page there may be of benefit.)
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white shadow said:

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Hey!

This may broaden your understanding: Tanya's Comprehensive Guide - D-mannose.

(In fact, the entire page there may be of benefit.)
.

Click to expand...

Thanks! I'll re-read a few more times, but I don't think it mentioned using it as a preventative treatment, but I supposed you could 'assume' it would be effective as such. Feeby generally doesn't demonstrate any 'forewarning' signs of a UTI brewing until she pees over the top of the litter box. By then, for her, the UTI is 'active' and would require antibiotics. So, I was hoping to use it either as pulse therapy or give her a daily 'maintenance' dose, and reduce the number of times she has to be on antibiotics.

I used it years ago to prevent UTIs in a dog who had a neurological condition which caused him to lose the use of the lower part of his body. Because he had to be expressed, the risk of UTIs was high and he never got one. I also use it myself. The one that I use would not be suitable for a cat, so I won't take up any more space with that and the one I used for the dog was from a mail order company which I don't recall. I have never used it with a cat; however, all of my uses of it were preventative. To be honest, once a UTI was in progress I would not trust it to cure it.

fionasmom said:

To be honest, once a UTI was in progress I would not trust it to cure it.

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Totally agree!!

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I saw this earlier today, thought it is too 'deep' for here, then thought 'why not?'....perhaps, between you and your Vet, well, who knows?

This was presented at a very large veterinary conference just last month. The author has his Diplomate and is at U of Wisconsin. So, IMO, it most likely represents the very latest/best thinking/practice.

Here you are: http://files.alfresco.mjh.group/alf...f-5ad47dc182e0/Urology-Wood-Recurrent-UTI.pdf.
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white shadow said:

I saw this earlier today, thought it is too 'deep' for here, then thought 'why not?'....perhaps, between you and your Vet, well, who knows?

Click to expand...

Good read, and I liked that it was fairly comprehensive in terms of many of the points it hits on I have seen scattered through numerous other articles I have read.

Doesn't do much to help pinpoint anything in particular about preventative treatment possibilities for Feeby, given all the variables. That is pretty much what I expected even before I began reading about various options. But, it might help somewhat in my next discussion with the vet.

Hi - sorry for belated reply - I just saw this notice.

Yes, I used D-Mannose for E.Coli related UTIs, and as far as I know, it worked.

My cat Mango was on high dose prednisolone and chlorambucil (plus, for supportive care, Cerenia, mirtazapine, and potassium) started in November 2015 for intestinal lymphoma. He'd had UTIs in the past, but starting in the end of 2017, he was getting them a lot more frequently, and by September of 2018, he'd get a new one as soon as the antibiotics were out of his system (so, basically, E.Coli every 3-4 weeks). Early on in the process, he did have an ultrasound to rule out stones. Also, all the UTIs were cultured as E. Coli.

Because of the lymphoma, stopping the prednisolone (which we thought was contributing to the UTI susceptibility) wasn't feasible, so I poked around the web, found recommendations for D.Mannose - asked my Vet what she though, and she looked into it, said it couldn't hurt, but she also wasn't sure if it would help either.

I used this version of D. Mannose ( ).

I didn't use it to cure the UTI, I started it when he was in the middle of the antibiotic regimen - I mixed 1/4 teaspoon in water, and syringe fed it to Mango (started out as 2 times a day for 10 days, and then cut back to 1 time a day (and kept him on it from then on). The plan was to see if it would prevent the E.Coli from coming back.

He was on the D.Mannose from October 2018 through April 2019 without any more UTIs (whereas he'd had about 8 in the six months prior). Unfortunately, I had to let him go in April of 2019 (he was 17.5 and really ill, probably from the lymphoma, but the vet thought it was possible that he also had a sarcoma in his jaw).

I didn't notice any side effects - however, Mango was on so many medications at that point that I don't think I could pinpoint which medication had caused which side effect. My guess would be that it's possible that the sugar in the D.Mannose could cause some tooth decay (if your cat has bad teeth... which, Mango did).

I chose the syringe feeding method rather than dumping it in his water bowl, because that was the only way I could be certain he was getting enough of D.Mannose (he was so good at taking all of his medication - very sweet and patient kitty), but if your cat is bad at taking meds, it might be more of a problem. I doubt there was any taste to it (when I gave Mango a medication that tasted awful, he would let me know).

K KarenF - thank you for replying! And, so sorry about Mango. That is the exact product I was looking at! I am hoping to use it as a preventative treatment, meaning that I would give a daily dosage to Feeby. I want to initially try adding it to her food - with the way she eats, it might work! If not, we'll figure it out!

She, too, was cleared in the past few months of stones, and the vet said her bladder looked good - it's just the UTIs which are relatively frequent now for about the past 1 1/2 years, after having had none for years and years previously.

Thanks again!

Just heard from my vet - he said: "Excellent idea on your part! Don't bother with the ones that have cranberries, just use pure D-mannose. It won't hurt her, even if it doesn't work, but it is certainly worth a try." He also said to get one specifically for cats as the dosing will be more accurate, and he was hoping it might also be better for palatability (although, I doubt that).

It's on!!

FeebysOwner said:

It's on!!

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Good luck!

I use D Mannose for my kitty with urinary issues. I have used it both as a preventative and also when he has an infection.

I use the powder formula from Now brands.
Mine is 1 t. is 2 grams. I give 1/8 t. 2x a day. I just mix it right into his food. But I have diluted it in water and given it in a syringe as well.

It works so very well. During a flare I may give the D Mannose up to 4x a day.