Is This Necesseraly Fip?

Noirele

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Did you ask how the tests could be negative and they still think it is FIP? The story your vet gave you last time is - to put it bluntly - is B.S. If there are no antibodies for corona virus appearing in your cat's system then I do not understand how she can possibly have FIP.
A negative coronavirus blood test does rule out coronavirus infection in an asymptomatic cat, but not FIP. With acute wet FIP, a cat could test negative, because there wasn't enough time to develop antibodies. I am kinda sure about that, sadly.
 
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Ivana90

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A negative coronavirus blood test does rule out coronavirus infection in an asymptomatic cat, but not FIP. With acute wet FIP, a cat could test negative, because there wasn't enough time to develop antibodies. I am kinda sure about that, sadly.
Sadly that is true. I just came home from third vrt. He tested water and he is 100% sure it is FIP. We fought so hard, I still can't believe it.
 

di and bob

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My heart cries for you and that sweet girl. Our hearts cannot accept something so unimaginable. I will pray for her. Just love her and be with her as much as you can, miracles still happen you know!
 
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Ivana90

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My heart cries for you and that sweet girl. Our hearts cannot accept something so unimaginable. I will pray for her. Just love her and be with her as much as you can, miracles still happen you know!
Thank you so much, I am under so much stress that I can't eat nor sleep properly . It may sound odd or crazy to someone but I just love her so so much and I consider her equal member of my family. It is so hard do cope with this terrifying diagnosis. She visited top 3 vets in the city and they all say the same thing. She is so innocent, why is this world so cruel.
 

FeebysOwner

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I have spent the entire morning trying to find information about FIP in cases where one test or another did not detect FCoV antibodies.

Here is what I found, in case you would want to read about it - and ask the vets if the details below (and in the corresponding link to the full article) confirm or deny that the FAStest covered the same testing parameters. The data below mentions the Rivalta test that I brought up to you before - which as I understand, is not the same as the FAStest.

Occasionally, an effusive FIP sample will appear to be antibody negative (Norris et al, 2005; Sparkes et al, 1991) because there is so much virus in the cat that all the antibody is bound to it and is not available to bind to the virus in the test (Meli, 2013). If this is suspected, send the effusion for an RT-PCR test: effusions from FIP cats are sometimes, strangely, negative by RT-PCR but in these FIP cats with negative antibody tests, the RT-PCR signal is usually huge (Meli, 2013).

In a case of effusive FIP, the antibody titre would usually be high, but it can be variable, especially if the test is performed on the effusion: false negative results can occur, especially with some of the less sensitive rapid immunomigration tests, therefore a FCoV antibody test is best performed on blood.

Summary
A cat with wet FIP should be FCoV seropositive, the total protein of the effusion must be over 35g/l and the albumin:globulin less than 0.4 (or at least less than 0.8), the AGP should be high (over 1500 micrograms/ml) and the cytology should reveal few nucleated cells which are mainly neutrophils and macrophages. A Rivalta test should be positive. Diagnosis can be confirmed by detecting FCoV in the macrophages in the effusion.


The presence of antibodies indicates that the cat has been infected with FCoV, the cause of FIP. Any FCoV antibody titre can occur in cases of wet or effusive FIP, but most cats with FIP have extremely high antibody titres (1280 or greater). Antibody titres of 0 are unusual in FIP cases and are usually considered as indicating that the cat does not have FIP. (However, if other parameters suggest a diagnosis of FIP, despite having an antibody titre of 0, then this is the one situation where FCoV RNA detection (RT-PCR), performed on a sample of the effusion, is diagnostic of FIP.

Feline Infectious Peritonitis and Coronavirus Web Site

Also, I am including the article below about a test that was introduced in the 2015 timeline that was supposed to be the most accurate diagnostic tool for FIP at that time.

I have not been able to tell if this test is an older version of what your vet performed, or if it is the same as, or an older version of, the Rivalta test mentioned above. (I am also still trying to determine if the above mentioned RT-PCR is one in the same with any of these other tests that are noted.)

https://idexxcom-live-b02da1e51e754...c75ac/feline-infectious-peritonitis-virus.pdf
 
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Ivana90

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I have spent the entire morning trying to find information about FIP in cases where one test or another did not detect FCoV antibodies.

Here is what I found, in case you would want to read about it - and ask the vets if the details below (and in the corresponding link to the full article) confirm or deny that the FAStest covered the same testing parameters. The data below mentions the Rivalta test that I brought up to you before - which as I understand, is not the same as the FAStest.

Occasionally, an effusive FIP sample will appear to be antibody negative (Norris et al, 2005; Sparkes et al, 1991) because there is so much virus in the cat that all the antibody is bound to it and is not available to bind to the virus in the test (Meli, 2013). If this is suspected, send the effusion for an RT-PCR test: effusions from FIP cats are sometimes, strangely, negative by RT-PCR but in these FIP cats with negative antibody tests, the RT-PCR signal is usually huge (Meli, 2013).

In a case of effusive FIP, the antibody titre would usually be high, but it can be variable, especially if the test is performed on the effusion: false negative results can occur, especially with some of the less sensitive rapid immunomigration tests, therefore a FCoV antibody test is best performed on blood.

Summary
A cat with wet FIP should be FCoV seropositive, the total protein of the effusion must be over 35g/l and the albumin:globulin less than 0.4 (or at least less than 0.8), the AGP should be high (over 1500 micrograms/ml) and the cytology should reveal few nucleated cells which are mainly neutrophils and macrophages. A Rivalta test should be positive. Diagnosis can be confirmed by detecting FCoV in the macrophages in the effusion.


The presence of antibodies indicates that the cat has been infected with FCoV, the cause of FIP. Any FCoV antibody titre can occur in cases of wet or effusive FIP, but most cats with FIP have extremely high antibody titres (1280 or greater). Antibody titres of 0 are unusual in FIP cases and are usually considered as indicating that the cat does not have FIP. (However, if other parameters suggest a diagnosis of FIP, despite having an antibody titre of 0, then this is the one situation where FCoV RNA detection (RT-PCR), performed on a sample of the effusion, is diagnostic of FIP.

Feline Infectious Peritonitis and Coronavirus Web Site

Also, I am including the article below about a test that was introduced in the 2015 timeline that was supposed to be the most accurate diagnostic tool for FIP at that time.

I have not been able to tell if this test is an older version of what your vet performed, or if it is the same as, or an older version of, the Rivalta test mentioned above. (I am also still trying to determine if the above mentioned RT-PCR is one in the same with any of these other tests that are noted.)

https://idexxcom-live-b02da1e51e754...c75ac/feline-infectious-peritonitis-virus.pdf
Thank you so so much for youe effort. They performed Rivalta test and it is positive, they did some bloodtest that indicate FIP. She struggled to eat last night and I found big lump on her troath. Her belly is filling more and more. We are going to put her to sleep tommorow and it breaks my heart. The pain is unexplicable, I just can't stop crying, we fought so hard and she was brave like a lioness. I love her too much. I hate this desease from bottom of my heart.
 
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Ivana90

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I am so sorry for you, your little girl, and for anything I may have done to give you false hope. :sniffle: :alright:
You did nothing but helping me. That illnes got us all fooled, she never had the chance to create antibodies, it grabed her so fast. She fell asleep for the last time few hours ago. My heart cries for her, I will never make peace with this. I whish that no cat ever get thi awful desease from hell. Thank you again for everything.
 

FeebysOwner

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TCS has a section called Crossing The Bridge, where members can honor and pay tribute to their lost loved ones.

If
/when you should feel like it, you are welcome to share with us any thoughts/memories, and pictures of your baby so that TCS will have a lasting homage to her that all of us can cherish.

Our hearts go out to you and your sweet angel.
 
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Ivana90

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TCS has a section called Crossing The Bridge, where members can honor and pay tribute to their lost loved ones.

If
/when you should feel like it, you are welcome to share with us any thoughts/memories, and pictures of your baby so that TCS will have a lasting homage to her that all of us can cherish.

Our hearts go out to you and your sweet angel.
Well I would love that...how can I do that?
 

Kflowers

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I'm so sorry for your loss. Know that she will always be with you and that she knows you did everything you could for her. Love never ends, it transcends the bounds of the physical and remains forever.

If you wish to post in crossing the bridge here is the addy Crossing the Bridge

or go to forums at that the top of this page and scroll down.
 

di and bob

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Why does God allow this horrible suffering and the pain to those who love them??!!
My heart breaks for you, for her the pain is over, she is at peace with knowing she was loved so very much by you. You will always have that bond of love between you, it is spiritual so will be eternal, "Death cannot take that which never dies" and that is love. May God bless you for your pain, and comfort you in this time of need......
 

FeebysOwner

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Well I would love that...how can I do that?
K Kflowers was kind enough to give you the link to Crossing the Bridge. Just click on it and it will lead you to that section.

Or, you can click on the overall "Forums" section (from the main header above) and scroll down to the group of links labeled "Living With Cats" - Crossing the Bridge is the second link under that group.
 
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